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. 2014 Apr 8;9(4):e94114. doi: 10.1371/journal.pone.0094114

Figure 5. The phenotypes of control and Memo KO embryos.

Figure 5

Memo +/− males and females were mated and the phenotypes of the Memo −/− (Memo KO) embryos were analyzed. A, Percentage of Memo KO embryos found dead with respect to total number of Memo KO embryos. B, percentage of living Memo KO embryos showing the indicated abnormality with respect to total number of living Memo KO embryos. In A and B, total sample numbers (n) for each stage are indicated at the bottom of each panel. C, Whole-mount view of control and Memo KO yolk sacs at E14.5. Scale bar, 4 mm. D, Whole-mount view of control and Memo KO embryos from E14.5 to E16.5. The sites of edema and bleeding frequently observed in Memo KO embryos are indicated as arrows and arrowheads, respectively. The Memo KO embryos shown in C and D were alive, except for E16.5. Scale bars, 4 mm. In all images, Memo KO is presented with the littermate control.