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. 2014 Feb 4;15(4):452–462. doi: 10.4161/cbt.27820

graphic file with name cbt-15-452-g1.jpg

Figure 1. acALY18 is derived from TRPC1. Western analysis of wild-type (WT) embryonic mouse fibroblasts (A) and TRPC1−/− embryonic mouse fibroblasts (B) treated with 25 nM thapsigargin and probed for acALY18. (C) The representative graph of acALY18 expression in WT (■) and TRPC1−/− (■) embryonic mouse fibroblasts normalized to GAPDH. (D) IL-1β secretion from WT (■) and TRPC1−/− (■) fibroblasts treated with 25 nM thapsigargin for 72 h.