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. 2014 Feb 18;97(4):397–404. doi: 10.1097/01.TP.0000440951.29757.bd

FIGURE 2.

FIGURE 2

PD study. Rate of ASKP1240 receptor occupancy in the low- and high-dose ASKP1240-treated normal and transplanted monkeys (A). Rate of ASKP1240 receptor occupancy in the 2.0 mg/kg ASKP1240-treated normal monkey group (B), 5.0 mg/kg ASKP1240-treated normal monkey group (C), 2.0 mg/kg ASKP1240-treated transplanted monkey group (D), and 5.0 mg/kg ASKP1240-treated transplanted monkey group (E). The representative MFI data show the ASKP1240 occupancy in the four different groups; the green line represents the controls (F).