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ASKP1240 immunohistochemical staining in normal and transplanted kidneys. Specific staining of ASKP1240 was observed in the transplanted kidney allograft (A) but not in the normal kidney (B), which suggests that CD40 expression was induced in the transplanted kidney, thereby affecting the CD40 occupancy rate and ASKP1240 serum concentration during ASKP1240 treatment.
