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. 2014 Apr 8;9(4):e94399. doi: 10.1371/journal.pone.0094399

Table 1. Clinicopathological Correlation of MAML2 Rearrangement in PMECs.

MAML2 rearrangement
Variables Positive (n = 21) Negative (n = 21) P
Median age [range] 33 [14–73] 60 [27–76] 0.001
Gender (M/F) 13/8 12/9 1.000
Tumor size [range], cm 3.0 [0.5–6.5] 3.0 [0.5–10.0] 0.693
TNM stage
I∼IIA 19 (90.5) 17 (81.0) 0.663
IIB∼IV 2 (9.5) 4 (19.0)
LN involvement
Yes 2 (9.5) 5 (23.8) 0.410
No 19 (90.5) 16 (76.2)
Intrathoracic invasion
Yes 4 (19.0) 6 (28.6) 0.719
No 17 (81.0) 15 (71.4)
Pathological grade
Low/Intermediate 21 (100.0) 12 (57.1) 0.001
High 0 (0.0) 9 (42.9)
Recurrence/metastasis
Yes 2 (9.5) 7 (33.3) 0.130
No 19 (90.5) 14 (66.7)

Abbreviations: MAML2, mastermind-like gene 2; PMECs, pulmonary mucoepidermoid carcinomas; TNM, tumor-nodal-metastasis; LN, lymph node.