Skip to main content
. 2014 Apr 8;9(4):e93920. doi: 10.1371/journal.pone.0093920

Table 2. In vitro (18 hrs) As+3, As+5 or MMA+3 Exposure and Effects on Mouse Bone marrow Cell Viability1 .

Treatments % Viability (Cellometer) % Annexin V negative/PI negative cells % Annexin V positive/PI negative cells % Annexin V negative/PI positive cells
Control 63.2+1.4 78.1+2.7 16.1+2.5 5.7+0.2
5 nM As+3 63.3+0.6 77.8+2.2 16.3+2.1 5.8+0.8
50 nM As+3 58.4+3.5 76.2+1.3 17.8+0.6 5.8+0.5
500 nM As+3 59.8+1.7 75.6+2.0 18.4+0.4 6.0+1.7
5 nM As+5 59.3+0.1 77.8+1.8 16.7+0.3 5.4+1.4
50 nM As+5 58.8+3.7 75.9+1.4 17.1+1.5 6.7+0.4
500 nM As+5 62.7+2.2 74.3+0.8 19.2+1.2 6.4+0.5
5 nM MMA+3 59.3+3.5 76.5+1.9 17.6+2.0 5.8+0.2
50 nM MMA+3 59.9+6.8 78.2+0.5 16.6+0.5 5.0+0.6
500 nM MMA+3 39.5+10.0* 52.0+2.5* 21.6+3.4* 26.4+2.2*
1

Bone marrow cells from three mice femurs were pooled and exposed to each treatment in triplicate. Results are Means + SD with statistical significance at *p≤0.05.