Table 3. Results from Biocarta pathway comparison between distant and non-malignant breast adipose tissue.
Biocarta pathway | Pathway description | Number of genes | LS permutation P value | KS permutation P value | Efron–Tibshirani GSA test P value |
---|---|---|---|---|---|
h_prc2 pathway | The PRC2 complex sets long-term gene silencing through modification of histone tails | 19 | 0.00148 | 0.02119 | <0.005 (+) |
h_eosinophils pathway | The role of eosinophils in the chemokine network of allergy | 7 | 0.00297 | 0.04015 | 0.035 (−) |
h_blymphocyte pathway | B lymphocyte cell surface molecules | 15 | 0.00401 | 0.20009 | 0.01 (−) |
h_il10 pathway | IL-10 anti-inflammatory signaling pathway | 15 | 0.02285 | 0.03816 | <0.005 (−) |
h_antisense pathway | RNA polymerase III transcription | 10 | 0.08858 | 0.02193 | <0.005 (+) |