Figure 6. Inhibition of Notch signaling impairs oocyte growth and decrease the expression of genes characteristic of the oocyte growth phase. (A) Diameters of oocytes isolated from 12.5 dpc ovarian tissues after 14 d of culture with or without DAPT. (B) Quantitative RT-PCR of 9 genes performed on oocytes isolated from 12.5 dpc ovarian tissues after 14 d. Graphs represent the average ± SD of samples in triplicate from 3 to 5 experiments.