Figure 7. Inhibition of Notch signaling reduces oocyte cyst breakdown and primordial follicle assembly. (A) Morphologies of 12.5 dpc ovarian tissues cultured for 4 d in the presence or absence of DAPT and transplanted under kidney capsule of 8–10-wk-old SCID Beige female mice for 10 d. (B) Representative tissue sections of the ovarian tissues from (A). (C) Percentage of oocytes in cyst and different classes of follicles in control and DAPT treated groups. (D) Number of oocytes for slices in control and DAPT treated groups.The results were presented as mean ± SD of at least 3 experiments. *P < 0.05;**P < 0.01.