Fig. 1.

Effect of short term-shear stress on water flux (J_v). At time 0 min, a hydrostatic pressure differential of 10 cm H₂O was applied, and a baseline was established after 60 min. Application of shear stress at 60 min triggered a time-dependent increase in J_v, which was blocked by a treatment of BAEC monolayers with 50 μM L-NMMA. Baseline J_v for static control, shear, and shear + L-NMMA were 1.97 ± 0.33 ×10⁻⁶ cm·s⁻¹ (n=7), 2.27 ± 0.23 ×10⁻⁶ cm·s⁻¹ (n=7), and 3.04 ± 0.55 ×10⁻⁶ cm·s⁻¹ (n=7), respectively. * P < 0.05, significant differences between shear and static monolayers. Data are presented as mean ± SEM.