Skip to main content
. Author manuscript; available in PMC: 2015 Apr 15.
Published in final edited form as: J Immunol. 2014 Mar 10;192(8):3548–3558. doi: 10.4049/jimmunol.1302241

Fig 4.

Fig 4

Human Eos promote human B cell proliferation and immunoglobulin secretion. A, CpG-stimulated B cells were cultured in the absence or presence of increasing numbers of Eos and proliferation was assessed by [3H]TdR-incorporation. B-D, B cells isolated from PB (B), tonsils (C), and spleens (D) were assessed for proliferation in culture with or without CpG stimulation and in the absence or presence of Eos. E-F, PB B cells were separated into naïve (E) and memory (F) cells and proliferation was assessed ± CpG stimulation in the absence or presence of Eos. G, CpG-stimulated B cells were cultured with or without Eos for 10 days and immunoglobulin levels were measured in the cell-free supernatants by ELISA. n.d., not detected. * p<0.05; ** p<0.01; *** p<0.001; n.s., not significant.