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Eos can augment B cell proliferation via a contact-independent mechanism(s). A, Proliferation of B cells either alone, in direct co-culture with B cells, or in the presence of Eos across a 0.4 μm transwell was assessed. B, Culture supernatants (supe) were collected from Eos and used to treat B cells in a proliferation assay ± CpG stimulation. ** p<0.01; *** p<0.001.
