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. Author manuscript; available in PMC: 2015 Jun 15.
Published in final edited form as: Int J Cancer. 2013 Dec 3;134(12):2853–2864. doi: 10.1002/ijc.28622

Figure 5. Mo-MDSC suppress T cell proliferation by NO production derived from iNOS.

Figure 5

A. Comparison of nitrities from G-MDSC and Mo-MDSC isolated from wild-type and iNOS−/− mice bearing 3LL tumors for 17 days (n=10). B–C. Mo-MDSC (B) and G-MDSC (C) were collected from wild-type and iNOS−/− mice bearing 3LL tumors and co-cultured with CFSE labeled T cells. Proliferation of T cells was established 72 hours later. The experiment was repeated a minimum of 3 times obtaining similar results. D. PNT production from each population was analyzed by nitrotyrosine ELISA (n=9). * p < 0.01; Non-statistical significant differences (ns): p > 0.05