. 2013 Dec 12;35(4):3755–3763. doi: 10.1007/s13277-013-1497-1

Table 2.

Association of CYB5R2 promoter methylation status and clinicopathological characteristics of NPC patients

	No. of patients	Promoter methylation status		P value
	No. of patients	Methylated	Unmethylated	P value
Age (years)				NS
< 60	37	30	7
≥ 60	13	10	3
Sex				NS
Male	35	28	7
Female	15	11	4
Cancer stage^a				NS
I	4	3	1
II	15	12	3
III	17	12	5
IV	14	12	2
Histological subtype				NS
Keratinizing squamous cell carcinoma	7	6	1
Non-keratinizing carcinoma	43	35	8
Lymph node metastasis				P < 0.05
Presence	33	33	0
Absence	17	10	7

Data are number of patients

NS not significant

^aAccording to the International Union Against Cancer (UICC)