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The effect of COX-2 on the expression of MMP-7. After LAC A549 cells were transfected with siCOX-2 adenovirus for 24 h, the expression levels of COX-2 and MMP-7 were detected by Real-time PCR (A, B) and Western blot assays (C-F). The expression of COX-2 and MMP-7 was significantly decreased in siCOX-2 group compared with the CON and NC groups (each **P<0.01), suggesting that COX-2 might upregulate the expression of MMP-7 in LAC cells.
