Table 5.
Functional modules related to the drug-colorectal cancer associations
| Database | Functional modules | p-value |
|---|---|---|
| BIOCARTA | GSK3 pathway | 7.29E-14 |
| KEGG | Endometrial cancer | 2.30E-11 |
| KEGG | Colorectal cancer | 4.32E-9 |
| KEGG, BIOCARTA, REACTOME | Toll like receptor pathway | 5.79E-9 |
| KEGG | Prostate cancer | 1.36E-6 |
| BIOCARTA | P53hypoxia pathway | 1.93E-6 |
| KEGG | Lung cancer | 2.30E-6 |
| KEGG | Glioma | 5.82E-6 |
| KEGG | Renal cell carcinoma | 8.40E-6 |
| KEGG | Melanoma | 9.01E-6 |
| KEGG | Chronic myeloid leukemia | 1.03E-5 |
| KEGG | VEGF signaling pathway | 1.26E-5 |
| KEGG | Innate Immune System | 1.29E-5 |
| KEGG | Fc epsilon RI signaling pathway | 1.52E-5 |
| REACTOME | Regulation of ornithine decarboxylase (ODC) | 4.28E-5 |
| KEGG | Pancreatic cancer | 1.74E-4 |
| KEGG | Wnt signaling pathway | 3.34E-4 |
| GO | Apoptosis | 1.54E-3 |
| KEGG | Neurotrophin signaling pathway | 1.62E-3 |