Table 1.
Description of the 120 incident cases of dementia.
| Dementia | ||||
|---|---|---|---|---|
|
| ||||
| n | (%) | m (SD) | ||
| Gender | Female | 68 | 56.7 | |
| Age at baseline | (years) | 120 | 78.4 (5.7) | |
| Education | Primary | 51 | 42.5 | |
| Middle school | 27 | 22.5 | ||
| High school | 21 | 17.5 | ||
| University | 21 | 17.5 | ||
| Smoking status | Current or Former | 44 | 36.7 | |
| Body Mass Index | Normal | 63 | 54.3 | |
| Overweight | 42 | 36.2 | ||
| Obese | 11 | 9.5 | ||
| Hypercholesterolemia | 61 | 51.3 | ||
| Hypertension | 69 | 57.5 | ||
| History of CVD | 45 | 37.5 | ||
| Diabetes | 16 | 13.3 | ||
| Alcohol (g/day) | <1 | 22 | 18.3 | |
| 1–36 g | 83 | 69.2 | ||
| >36 g | 15 | 12.5 | ||
| Living status | Alone | 47 | 39.2 | |
| Apo E | At least 1 Apoε4 allele | 44 | 36.7 | |
| IADL | At least 1 | 32 | 26.7 | |
| Depression | CES-D score <16 or antidepressants | 53 | 44.2 | |
| MCI status | 85 | 72.6 | ||
| MMSE* (n=120) | 120 | 25.6 (1.99) | ||
| BVRT* (n=116) | 116 | 9.8 (2.72) | ||
| IST* (n=117) | 117 | 24.8 (5.7) | ||
| Plasma Aβ levels | ||||
| Aβ40 | pg/ml | 120 | 246.0 (56.39) | |
| Aβ42 | pg/ml | 120 | 39.8 (10.55) | |
| Aβn-40 | pg/ml | 120 | 269.4 (62.33) | |
| Aβn-42 | pg/ml | 120 | 27.7 (8.32) | |
| Aβ42/Aβ40 ratio | 120 | 0.2 (0.05) | ||
| Aβn-42/Aβn-40 ratio | 120 | 0.1 (0.03) | ||
*
Data are presented for the 120 demented subjects, except for the BVRT (n=116) and the IST (n=117).
SD: Standard Deviation; CVD: Cardiovascular Disease; Apo E: Apo lipoprotein E; IADL: Instrumental Activities of Daily Living; CES-D: Center for Epidemiologic Studies Depression Scale; MCI: Mild Cognitive Impairment; MMSE: Mini Mental State Examination; BVRT: Benton Visual Retention Test; IST: Isaacs Set Test.