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. 2014 Apr 3;94(4):586–598. doi: 10.1016/j.ajhg.2014.03.008

Figure 4.

Figure 4

Proposed Molecular Model of Transcriptional Control of BLK Expression

A proposed model depicting how the lupus-associated risk alleles at the P1 and P2 sites alter BLK transcription (A) and a proposed model representing ways in which BLK might affect B cell development and control of autoimmune responses (B) are shown.