Table 1.
Characteristics of HIV-positive adults newly hospitalized from April to September 2010, overall and according to the underlying cause of hospitalization, IeDEA West Africa Collaboration (N=823)
| All causes | AIDS | Other infections | Other diseases | Non-specific illnessa | |
|---|---|---|---|---|---|
|
|
|||||
| (n=823) | (n=445, 54.0%) | (n=268, 32.5%) | (n=62, 7.5%) | (n=49, 6.0%) | |
| Median age (years) (interquartile range) | 40 (33–48) | 39 (34–47) | 40 (32–47) | 40 (34–53) | 40 (34–47) |
| Women (%) | 58 | 56 | 62 | 61 | 55 |
| HIV type (%) | |||||
| 1 | 94 | 94 | 93 | 98 | 92 |
| 2 | 4 | 4 | 5 | 0 | 6 |
| 1 +2 | 2 | 2 | 2 | 2 | 2 |
| Diagnostic of HIV (%) | |||||
| During hospitalization | 24 | 25 | 25 | 11 | 20 |
| <6 months before hospitalization | 42 | 48 | 36 | 29 | 35 |
| ≥6 months before hospitalization | 34 | 27 | 39 | 60 | 45 |
| Known duration of HIV infection if HIV diagnosed before hospitalization (n=623) (months) (interquartile range) | 3.7 (0.6–31.7) | 2.1 (0.5–17.8) | 7.6 (0.7–38.8) | 18.6 (1.7–52.5) | 10.3 (1.2–39.6) |
| WHO stage at entry (%) | |||||
| 4 | 54 | 80 | 23 | 35 | 12 |
| 3 | 40 | 19 | 66 | 48 | 80 |
| 2 or 1 | 6 | 1 | 11 | 17 | 8 |
| Median body mass index (kg/m2) (interquartile range) | 16.8 (14.5–19.6) | 16.5 (14.3–19.1) | 16.9 (14.2–19.6) | 18.3 (16.1–21.4) | 17.7 (14.5–21.5) |
| Median haemoglobinemia (g/l) (interquartile range) | 9.0 (7.0–10.0) | 8.0 (7.0–10.0) | 8.0 (6.0–10.0) | 10.0 (8.0–11.0) | 8.0 (6.0–10.0) |
| Median last CD4+cell countb (n=625) (/mm3) (interquartile range) | 75 (25–177) | 58 (19–128) | 88 (28–231) | 154 (46–333) | 106 (54–193) |
| History of cotrimoxazole prophylaxis (%) | 52 | 49 | 51 | 65 | 60 |
| History of ART use (%) | 48 | 45 | 45 | 71 | 59 |
| Median time since first ART (n=388) (months) (interquartile range) | 13.2 (2.0–44.5) | 5.1 (1.3–31.1) | 25.2 (3.3–57.2) | 30.4 (2.9–56.6) | 14.7 (3.6–38.7) |
| Median CD4+cell count at ART initiation (n=300) (/mm3) (interquartile range) | 90 (32–176) | 84 (29–165) | 90 (32–198) | 118 (61–173) | 97 (50–193) |
| Median duration of hospitalization (days) (interquartile range) | 13 (7–22) | 15 (8–27) | 11 (7–19) | 13 (6–20) | 9 (6–12) |
| Death in hospital (n=315) (%) | 38 | 46 | 34 | 23 | 16 |
HIV: human immunodeficiency virus; ART: combination antiretroviral treatment; WHO: World Health Organization.
a
Non-specific diseases: symptomatic diagnosis, non-specific WHO stage 3 events (weight loss>10%, chronic diarrhoea, persistent fever);
b
median time between date of hospitalization and last CD4 count: two days (IQR: −21 to +7).