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. Author manuscript; available in PMC: 2015 May 1.
Published in final edited form as: Behav Brain Res. 2014 Feb 5;264:34–42. doi: 10.1016/j.bbr.2014.01.044

Figure 3.

Figure 3

Hippocampal Aβ42 increased with age in APP/PSEN1 mice. A) Soluble Aβ42 increased with age, with significantly elevated amounts in mice aged 20 months (p = .05). B) Total Aβ42 was significantly elevated at 9 (p < .001) and 20 (p < .001) months compared to 3 months. ASC treated mice had significantly less Aβ42 (p < .05), though this result was likely due to variability in total Aβ42 measurements among mice. Values are mean ± SEM. n = 6 for each age group. * p < .05 compared to 3 mo; *** p < .001 compared to 3 mo.