Table 3.
Prognostic value of CTC and object levels at baseline.
| Factor | Cut-Off | Median PFS | p | Median OS | p |
|---|---|---|---|---|---|
| INTACT CTC | 5 | 4.1 vs. 7.6 | 0.034 * | 4.6 vs. 10.7 | 0.008 * |
| APOPTOTIC CTC | 2 | 3.4 vs. 7.6 | 0.017 * | 3.6 vs. 10.5 | 0.001 * |
| CK FRAGMENTS | 2 | 3.4 vs. 8.7 | 0.035 * | 5.4 vs. 11.2 | 0.10 |
| CK+ CD45+ | 2 | 6.5 vs. 6.8 | 0.59 | 7.3 vs. 9.6 | 0.86 |
| BLOOD CELLS | 17 | 6.7 vs. 7.1 | 0.60 | 9.1 vs. 9.6 | 0.97 |
| INTACT/APOPTOTIC CTC | 2 | 4.3 vs. 8.4 | 0.006 * | 5.7 vs. 10.9 | 0.014 * |
| INTACT/APOPTOTIC CTC + CK+ FRAGMENTS | 5 | 4.1 vs. 8.5 | 0.003 * | 6.5 vs. 10.9 | 0.026 * |
PFS, progression free-survival; OS, overall survival; * p ≤ 0.05.