Table 1.
Detailed chronological histopathological results in the lungs.
| Lesions |
|||||
|---|---|---|---|---|---|
| Groups | Time (D.p.i.) | Leucocytes infiltrates | Cells increased | Congestion | Haemorragic alveolitis |
| N | 4 | 0 | 0 | 0 | 0 |
| 7 | 0 | 0 | 0 | 0 | |
| 13 | 0 | 0 | 0 | 0 | |
| 30 | 0 | 0 | 0 | 0 | |
| P. y | 4 | 0 | 0 | 0 | 0 |
| 7 | 0 | 5/5 | 0 | 0 | |
| 13 | 0 | 3/3 | 3/3 | 0 | |
| 30 | 0 | 3/3 | 3/3 | 0 | |
| P. c | 13 | 0 | 3/3 | 3/3 | 0 |
| 30 | 0 | 4/4 | 4/4 | 4/4 | |
| P. y + L. s | 4 | 0 | 0 | 0 | 0 |
| 7 | 2/7 | 7/7 | 0 | 0 | |
| 13 | 0 | 3/3 | 3/3 | 0 | |
| 30 | 0 | 2/2 | 2/2 | 0 | |
| P. c + L. s | 13 | 0 | 2/2 | 2/2 | 0 |
| 30 | 0 | 3/3 | 3/3 | 3/3 | |
| L. s | 4 | 0 | 0 | 0 | 0 |
| 7 | 5/7 | 0 | 0 | 0 | |
| 13 | 0 | 0 | 0 | 0 | |
| 30 | 0 | 0 | 0 | 0 | |
The different groups of mice are listed in column 1. Time of necropsies is indicated in the second column. For each lesion observed in the lungs, numbers indicate the number of mice showing the lesions/total number of studied mice. D.p.i.: Day post-inoculation; Alv cells inc: increase in the number of alveolar cells; uninf: uninfected mice; L. s: mice infected by L. sigmodontis; P. y: mice infected by P. yoelii; P. y + L. s: mice co-infected by L. sigmodontis and P. yoelii; P. c: mice infected by P. chabaudi; P. c + L. s: mice co-infected by L. sigmodontis and P. chabaudi.