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. 2014 Mar 20;2014:294150. doi: 10.1155/2014/294150

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Copyright © 2014 Ming Zhang et al.

This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Myosin Va expression regulated by BMP-2. (a) qRT-PCR analysis revealed mRNA upregulation of the myosin Va gene associated with adenoviral-mediated BMP-2 overexpression in rat VSMCs. (b) Myosin Va expression reflects a dose-dependent response to BMP-2 administration. (c) Immunofluorescent assay characterizes actin and myosin Va expression. Myosin Va proteins were abundantly distributed in the cytoplasm of cells binding closed actin in BMP-2 overexpressing VSMCs, compared to control (which manifested only weakly positive signals).