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. Author manuscript; available in PMC: 2014 Apr 9.
Published in final edited form as: J Phys Chem B. 2010 May 13;114(18):5971–5982. doi: 10.1021/jp9114546

Figure 1.

Figure 1

Characteristic membrane structural features are associated with the activation and locomotion of mast cells. Images A–C are AFM topography, deflection, and zoom-in images of a resting BMMC with its characteristic villi structures. Images D–F present an IgE-sensitized BMMC activated by DNP-BSA immobilized on the surface, showing characteristic membrane ridges. The images in G–H display an anti-DNP IgE-sensitized BMMC spreading on a DNP-BSA coated surface, with characteristic locomotion structures of lamellipodia and filopodia and characteristic activation structures of membrane ridges. Scale bars: 1 µm.