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. 2012 Dec 18;29(3):1094–1100. doi: 10.3892/or.2012.2198

Figure 1.

Figure 1

Effect of PF-02341066 on NSCLC cell lines. (A) Concentration of PF-02341066 necessary to inhibit clonogenic growth by 50% was determined by clonogenic surviving assay. (B) H2228 cells were treated with PF-02341066 for 4 h after which the drug was removed from the culturing medium. Samples were collected at the times noted. (C-E) H3122, H460 and A549 cells were treated with HGF (50 ng/ml) in the presence or absence of PF-02341066, and samples were collected as indicated for western blot analysis.