Figure 2.

Effect of radiation and PF-02341066 on NSCLC cells. Cells were grown to 70% confluence prior to treatment with PF-02341066 for 2 h and then cells were irradiated with increasing doses of radiation (2, 4, 6 and 8 Gy). Cells were then washed, trypsinized and plated for colony formation assay. (A) H460 cells (100 nM); (B) A549 cells (100 nM); (C) H2228 cells (13 nM); (D) H3122 cells (21 nM) and (E) H1993 cells (3.8 nM).