Table 2. Naranjo adverse drug reactions probability scale evaluation for case report.
Yes | No | Don't know | Score | |
---|---|---|---|---|
1. Are there previous conclusive reports of this Reaction? | Yes | +1 | ||
2. Did the adverse event appear after the Suspected drug was administered? | Yes | +2 | ||
3. Did the adverse reaction improve when the Drug was discontinued, or a specific antagonist Was administered? | Yes | +1 | ||
4. Did the adverse reaction reappear when the Drug was readministered? | N/A | 0 | ||
5. Are there alternative causes (other than the drug) that could on their own Have caused the reaction? | Yes | −1 | ||
6. Did the reaction reappear when a placebo Was given? | N/A | 0 | ||
7. Was the drug detected in the blood (or other fluids) in concentrations known to be toxic? | N/A | 0 | ||
8. Was the reaction more severe when the dose Was increased, or less severe when the dose Was decreased? | N/A | 0 | ||
9. Did the patient have a similar reaction to the Same or similar drug in any previous exposure? | No | 0 | ||
10. Was the adverse event confirmed by any Objective evidence? | Yes | +1 | ||
TOTAL | 4 |
Scale: >8 = highly probable; 5–8 = probable; 1–4 = possible; 0 = doubtful