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. 2011 Nov 8;1(4):e106. doi: 10.4081/cp.2011.e106

Table 1. Review literature of pemetrexed pneumonitis/lung injury.

Cases/Authors Biopsy(Y/N) Radiation(Y/N) No of cycles Died(Y/N) Severity* Treatment X ray Resolution Time of pneumonitis (after last dose)
Nagata, et al.2 No No 1 Yes Grade 5 Steroids None 4 wks
Sakamoto, et al.8 Yes No 1 Yes Grade 5 Steroids Unknown 1 day
Loriot, et al.11 No No 5 No Grade 3 Steroids Yes 3 days
Kim Ho, et al.1 Yes No 4 No Grade 3 Steroids Yes Few days
*

Severity grade based on common terminology criteria for adverse events (CTCAE) v 4.