Table 1. Review literature of pemetrexed pneumonitis/lung injury.
Cases/Authors | Biopsy(Y/N) | Radiation(Y/N) | No of cycles | Died(Y/N) | Severity* | Treatment | X ray Resolution | Time of pneumonitis (after last dose) |
---|---|---|---|---|---|---|---|---|
Nagata, et al.2 | No | No | 1 | Yes | Grade 5 | Steroids | None | 4 wks |
Sakamoto, et al.8 | Yes | No | 1 | Yes | Grade 5 | Steroids | Unknown | 1 day |
Loriot, et al.11 | No | No | 5 | No | Grade 3 | Steroids | Yes | 3 days |
Kim Ho, et al.1 | Yes | No | 4 | No | Grade 3 | Steroids | Yes | Few days |
Severity grade based on common terminology criteria for adverse events (CTCAE) v 4.