Table 1. Baseline Characteristics of the US Patients from the Global Orthopedic Registry (GLORY, N = 3,755).
| Unadjusted | Adjusted with Propensity Score Weighting | |||||
| LMWH (N = 1,561) | Warfarin (N = 2,194) | P Value | LMWH (N = 1,561) | Warfarin (N = 2,194) | P Value | |
| Year of surgery | 0.006 | 0.99 | ||||
| 2001 | 12.9 | 14.0 | 13.8 | 13.8 | ||
| 2002 | 37.9 | 33.4 | 35.2 | 35.1 | ||
| 2003 | 32.1 | 36.8 | 34.4 | 34.7 | ||
| 2004 | 17.1 | 15.8 | 16.6 | 16.4 | ||
| Age in years | 0.002 | 0.99 | ||||
| 18–54 | 13.7 | 18.2 | 16.3 | 16.2 | ||
| 55–64 | 23.9 | 21.8 | 22.8 | 22.8 | ||
| 65–74 | 34.3 | 33.9 | 33.6 | 33.9 | ||
| 75+ | 28.1 | 26.1 | 27.3 | 27.1 | ||
| Joint | <0.001 | 0.82 | ||||
| Hip | 31.1 | 45.9 | 40.4 | 40.0 | ||
| Knee | 68.9 | 54.2 | 59.6 | 60.0 | ||
| ASA scores | 0.002 | 0.86 | ||||
| No chronic conditions | 12.7 | 16.1 | 15.6 | 15.0 | ||
| Mild chronic conditions | 57.5 | 58.3 | 57.9 | 58.2 | ||
| Severe or moribound | 29.8 | 25.6 | 26.4 | 26.8 | ||
| Sex | 0.67 | 0.89 | ||||
| Male | 41.1 | 41.8 | 41.7 | 41.5 | ||
| Female | 58.9 | 58.2 | 58.3 | 58.5 | ||
| Body mass index (BMI) | 0.41 | 0.99 | ||||
| Under Weight | 0.5 | 0.6 | 0.6 | 0.6 | ||
| Norm Weight | 15.2 | 16.2 | 16.3 | 16.3 | ||
| Over Weight | 33.7 | 35.6 | 34.5 | 34.6 | ||
| Obese | 50.6 | 47.6 | 48.6 | 48.5 | ||
| Length of surgery | <0.001 | 0.86 | ||||
| <2 Hours | 91.6 | 81.4 | 86.7 | 87.1 | ||
| 2–4 Hours | 8.3 | 18.3 | 13.1 | 12.8 | ||
| >4 Hours† | 0.1 | 0.3 | 0.2 | 0.1 | ||
| Prior conditions | <0.001 | 0.75 | ||||
| No | 86.4 | 81.0 | 82.7 | 83.2 | ||
| Yes | 13.6 | 19.0 | 17.3 | 16.8 | ||
| Antibiotics use | 0.004 | 0.87 | ||||
| None | 0.5 | 1.6 | 1.1 | 1.1 | ||
| Prophylaxis only | 97.9 | 96.4 | 96.6 | 96.9 | ||
| Additional Indication | 1.7 | 2.0 | 2.3 | 2.0 | ||
ASA, American society of Anesthesiologists; LMWH, low molecular weight heparin.