Table 2. Comparison of Outcomes from the US Study Population of the Global Orthopedic Registry (GLORY).
| LMWH†(N = 1,561) | Warfarin† (N = 2,194) | Odds Ratio*(95% CI) | P Value | |
| Length of stay, median (IQR) | 3 (3–5) | 4 (3–4) | 0.98 (0.93, 1.03) | 0.40 |
| General complications | 48 (3.1) | 58 (2.6) | 1.41 (0.96, 2.07) | 0.08 |
| Cardiac | 9 (0.6) | 11 (0.5) | ||
| Medical | 16 (1.0) | 19 (0.9) | ||
| Surgical | 25 (1.6) | 31 (1.4) | ||
| Symptomatic VTE | 23 (1.5) | 19 (0.9) | 1.72 (0.93, 3.17) | 0.08 |
| Blood transfusion | 459 (29.4) | 483 (22.0) | 1.75 (1.51, 2.04) | <.001 |
| Volume (ml), mean (SD) | 614 (371) | 524 (227) | <.001 | |
| Bleeding | 97 (6.2) | 45 (2.1) | 3.82 (2.64, 5.52) | <.001 |
| Bleeding Complications | 13 (0.8) | 6 (0.3) | 2.95 (1.10, 7.89) | 0.03 |
| Surgical site infection | 25 (1.6) | 13 (0.6) | 2.79 (1.42, 5.45) | 0.003 |
| Superficial infection | 20 (1.3) | 9 (0.4) | 3.47 (1.53, 7.84) | 0.003 |
| Deep infection | 5 (0.4) | 4 (0.2) | ||
| Reoperation | 38 (2.3) | 28 (1.3) | 1.77 (1.07, 2.93) | 0.03 |
| Due to infection | 11 (0.7) | 11 (0.5) |
LMWH: low molecular weight heparin; IQR: inter quartile range; SD: standard deviation; CI, confidence interval; VTE: venous thromboembolism.
*LMWH vs. Warfarin.
†
Values are given as the number of patients with the percentage in parentheses, unless otherwise indicated.