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. 2014 Apr 9;9(4):e94092. doi: 10.1371/journal.pone.0094092

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© 2014 Li et al

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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Neonatal cardiofibroblasts from EPHX2^−/− or control mice were treated with 1 μM AngII and/or 1 μM sEH inhibitor (TUPS) for 24 h. Real-time PCR analysis of mRNA expression of collagen-synthesis–related genes and inflammatory factors. (A) COL1A1; (B) TGFβ1; (C) CTGF; (D) lysyl oxidase; (E) MCP-1 and (F) IL-6. Data are mean±SEM from 3 independent experiments (*, P<0.05).