Table 2. Variation of active site size and depth in members of the PTP family.
Volume (Å3) | Average depth (Å) | |
Bd1204 | 987 | 7.7 |
PhyAsr | 5370 | 14.9 |
PhyAmm D1 | 4862 | 13.0 |
PhyAmm D2 | 7333 | 17.0 |
PTEN | 2207 | 9.8 |
PTP1B | 2049 | 9.6 |
VHR | 967 | 8.7 |
Volume and average depth were calculated using the PDBsum server [34]. PhyAsr – Selenomonas ruminantium phytase, PhyAmm D1– N-terminal repeat of Mitsuokella multacida phytase, PhyAmm D – N-terminal repeat of M. multacida phytase, PTEN - Phosphatase and Tensin Homolog, PTP1B – Protein Tyrosine Phosphatase 1B, VHR - Vaccinia VH1 related dual specificity phosphatase.