Figure 3. ADA increases proliferation and IFN-γ secretion in co-cultures of HIV-inactivated-pulsed DC and autologous T cells of HIV-1-infected individuals. (A) T-cell proliferation in a 7 d assay, measured as c.p.m. of [³H]-thymidine incorporation during last 18 h of co-culture in absence (white columns) or presence (black columns) of ADA (B) IFN-γ secretion in absence (white), or presence (black) of ADA at day 2 of co-culture of T cells with DC pulsed with inactivated HIV-1 BaL (30 min heat inactivated). Bars indicated the mean of proliferation and IFN-γ secretion, respectively, and error bars represent the SEM from the mean of the replicates (n = 8).