Table 2.
Evaluation of IVF and Participant Characteristics on IVF Failures in Brigham and Women’s Hospital IVF Study, for Mixed and Transitional Models Assuming Common Covariate Effects on IVF Failure Types
| IVF and Participant Characteristics | Mixed Model | Transitional Model |
|---|---|---|
| OR (95% CI) | OR (95% CI) | |
| Intercepts | ||
| Implantation failure | 1.00 (referent) | 1.00 (referent) |
| Chemical pregnancy | 0.21 (0.18, 0.24) | 0.23 (0.19, 0.28) |
| SAB | 0.20 (0.17, 0.24) | 0.21 (0.17, 0.27) |
| Gonadotropin dose | 1.26 (1.17, 1.36) | 1.27 (1.18, 1.37) |
| Embryos transferred | 0.73 (0.68, 0.78) | 0.73 (0.68, 0.78) |
| Previous livebirth | 0.81 (0.69, 0.95) | 0.80 (0.68, 0.94) |
| Down regulation | 0.79 (0.67, 0.92) | 0.78 (0.66, 0.91) |
| ICSI | 0.99 (0.86, 1.14) | 1.00 (0.87, 1.15) |
| BMI Categories | ||
| < 18.5 | 1.07 (0.73, 1.56) | 1.07 (0.73, 1.57) |
| 18.5 – 25 | 1.00 (referent) | 1.00 (referent) |
| 25 – 30 | 1.03 (0.87, 1.22) | 1.03 (0.87, 1.22) |
| > 30 | 1.00 (0.80, 1.25) | 1.01 (0.80, 1.26) |
| Age Categories | ||
| < 35 | 1.00 (referent) | 1.00 (referent) |
| 35 – 37 | 1.09 (0.92, 1.30) | 1.09 (0.92, 1.30) |
| 38 – 40 | 1.58 (1.31, 1.90) | 1.59 (1.32, 1.92) |
| > 40 | 3.42 (2.67, 4.36) | 3.49 (2.73, 4.47) |
|
| ||
| AIC | 7679.0 | 7694.0 |
IVF=in vitro fertilization; OR=odds ratio; CI=confidence interval; ICSI=intracytoplasmic sperm injection; BMI=body mass index; SAB=spontaneous abortion; AIC=Akaike’s Information Criterion