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The effect of losartan (Los), metformin (Met), Nω-nitro-L-arginine methyl ester (L-NAME) or splitomicin (SP) on AngII type 1 (AT1R, A) and type 2 (AT2R, B) receptors in cell hypertrophy. Western blot data were normalized to actin and expressed as fold change relative to control groups. *P < 0.05 versus control; +P < 0.05 versus Met. n = 6–8 per group.
