Table 1.
Sample Characteristics
| Clinical Diagnosis | p-value | ||||||
|---|---|---|---|---|---|---|---|
| Control (n=44) | MCI (n=13) | Dementia (n=129) | Overall differences | Control vs. MCI | Control vs. Dementia | MCI vs. Dementia | |
| Variables Used in Establishing Clinical Diagnoses | |||||||
| Age (years) | 72.9 (11.5) | 77.0 (7.1) | 78.2 (7.9) | .132 | .234 | .050 | .602 |
| Education (years) | 15.1 (2.9) | 13.7 (3.3) | 12.9 (2.7) | .012 | .212 | .004 | .293 |
| Gender (% female) | 84.1 | 46.2 | 62.8 | .009 | .039 | .009 | .516 |
| MMSE | 29.4 (0.8) | 27.0 (1.4) | 23.1 (4.1) | <.001 | <.001 | <.001 | <.001 |
| Mini-Cog | 3.8 (0.6) | 1.9 (1.1) | 1.1 (0.9) | <.001 | <.001 | <.001 | .006 |
| Animal Naming (#/min) | 15.5 (3.6) | 14.7 (3.0) | 9.8 (3.7) | <.001 | 0.848 | <.001 | <.001 |
| 3-word Delayed Recall | 2.8 (0.6) | 1.2 (0.9) | 0.5 (0.7) | <.001 | <.001 | <.001 | .003 |
| Clock Draw (% abnormal) | 0 | 30.8 | 45.2 | <.001 | .056 | <.001 | .561 |
| Variables Under Study | |||||||
| AD8 | 1.1 (1.4) | 3.7 (1.7) | 5.2 (1.7) | <.001 | <.001 | <.001 | .008 |
| IQCODE | 3.1 (0.4) | 3.4 (0.5) | 3.9 (0.6) | <.001 | .002 | <.001 | <.001 |
Note: MCI = mild cognitive impairment; MMSE = Mini-mental State Exam, IQCODE = Informant Questionnaire on Cognitive Decline in the Elderly