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. Author manuscript; available in PMC: 2014 Apr 9.
Published in final edited form as: J Pharm Sci. 2012 Nov 28;102(2):352–364. doi: 10.1002/jps.23393

Figure 9.

Figure 9

Effect of MDA7 formulated in HPβCD, liposomes and micellar preparation administered by i.v. injection on tactile allodynia in a spinal nerve ligation neuropathic pain model at a dose of 10 mg/kg. MDA7 effects were greatest in HPβCD ≥ micellar> liposomes preparations at increasing the paw withdrawal threshold of the nerve-injured paw. **P<0.01, *P<0.05 versus corresponding vehicle. +P<0.05 versus MDA7 in HPβCD or in micellar preparations (two-way analysis of variance followed by Student-Newman-Keuls multiple comparisons test).