. Author manuscript; available in PMC: 2014 Apr 9.

Published in final edited form as: J Pharm Sci. 2012 Nov 28;102(2):352–364. doi: 10.1002/jps.23393

Table 1.

¹H NMR chemical shifts (δ in ppm) and changes (Δδ in ppm) of HPβCD protons upon complexation of MDA7 at 0.5 molar ratio in an equimolar solution of D₂O and methanol-d₄ at 300 K.

HPβCD protons	δ free (ppm)	δ complex (ppm)	Δδ (ppm)	MDA7 protons	δ free (ppm)	δ complex (ppm)	Δδ (ppm)
H1	5.024	5.014	−0.01	Ha	6.5745	6.6370	0.0625
H5	3.846	3.805	−0.041	Ha’	6.5745	6.6540	0.0795
CH_{3 HPβCD}	1.144	1.141	−0.003	Hc	4.1700	4.1270	−0.0430
				Hc’	4.1700	4.1060	−0.0640
				Hb	4.6175	4.6285	0.0110
				Hb’	4.6175	4.6230	0.0055
				CH₃	1.439	1.430	−0.009