Figure 2.

Associations between component scores and mean caudate DaT binding. Associations of latent variable (LV) scores extracted from the nodal strength data with nigrostriatal dopaminergic function measured by ¹²³I-FP-CIT SPECT (mean caudate SBR ratios). Positive associations (^*p < 0.05) were found for the Ist (“global/motor”) and IIIrd (“executive”) LVs. Corresponding loading maps are depicted in brain space, reflecting the relevance of the nodes (spheres) for a particular LV, the magnitude of which is represented by nodal size. Positive loading values are depicted as red spheres, whereas negative ones are shown in blue.