Figure 2.

Averaged (±s.d.) time course of radioactivity in cerebellum (open circles), hippocampus (open squares), thalamus (black triangles), striatum (black circles), cingulate cortex (open triangles), and pons (black squares) obtained from [¹¹C]ITDM-PET in baseline (A) and blocking (B) studies, respectively. All data are expressed as the standardized uptake value (SUV). [¹¹C]ITDM, N-[4-[6-(isopropylamino)-pyrimidin-4-yl]-1,3-thiazol-2-yl]-N-methyl-4-[¹¹C]-methylbenzamide; PET, positron emission tomography.