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. 2014 Jan 8;34(4):606–612. doi: 10.1038/jcbfm.2013.243

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Copyright © 2014 International Society for Cerebral Blood Flow & Metabolism, Inc.

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Representative [¹¹C]ITDM-PET images of the brains of noncarrier (A) and R6/2 (B) mice and magnetic resonance imaging (MRI) templates of mouse brain (C). The PET images displayed here reflect the radioactivity summed from 0 to 90 minutes after injection. Abbreviations are as follows: Ce, cerebellum; Po, pons; Th, thalamus; St, striatum. The color scale represents the distribution volume ratio (DVR). [¹¹C]ITDM, N-[4-[6-(isopropylamino)-pyrimidin-4-yl]-1,3-thiazol-2-yl]-N-methyl-4-[¹¹C]-methylbenzamide; PET, positron emission tomography.