Figure 6.
Validation of transgene expression in striatonigral but not striatopallidal MSNs in D1-ChETA line 1 mice. (A,B) Confocal images in brain slices from D1-EGFP/Drd1a-ChETA double transgenic mice. (A) Substantia nigra pars reticulata (SNr) region showing anti-EGFP (Ai), native tdTomato fluorescence (Aii), and the merged image (Aiii). (B) Images from the dorsal striatum (DStr) region. (C,D) Confocal images in brain slices from D2-EGFP/D1-ChETA double transgenic mice. (C) SNr/VTA boundary showing anti-EGFP (Ci), native tdTomato fluorescence (Cii), and the merged image (Ciii). (D) Images from the DStr region.