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. 2014 Mar 20;4(6):629–641. doi: 10.7150/thno.8518

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© Ivyspring International Publisher. This is an open-access article distributed under the terms of the Creative Commons License (http://creativecommons.org/licenses/by-nc-nd/3.0/). Reproduction is permitted for personal, noncommercial use, provided that the article is in whole, unmodified, and properly cited.

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Accumulation of gold nanorods in the ankle of an arthritic mouse. Top row: anatomic optoacoustic images acquired at (A) 800 nm illumination wavelength, (B) overlayed with the signal coming from AuNR-PEG (yellow scale) or (C) with oxygenated hemoglobin signal (red scale). Bottom row: anatomic optoacoustic image acquired at (D) 800 nm illumination wavelength, (E) overlayed with the signal coming from AuNR-dPGS (yellow) or (F) with oxygenated hemoglobin signal (red scale). (G) Photograph of a mouse leg indicating the scanning region (solid lines) with the corresponding imaging plane displayed in the left panels (dotted line).