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. Author manuscript; available in PMC: 2014 Apr 10.
Published in final edited form as: Nat Protoc. 2013 Sep 19;8(10):2006–2021. doi: 10.1038/nprot.2013.124

Table 1.

Problem solving.

Problem Possible Reason Solution
Incomplete consumption of reward Animal insufficiently food restricted Decrease weight as regulations permit
Animal insufficiently habituated to reward Provide reward in home cage for additional days
Unstable or poor performance Low or excessive motivation Closer attention to weight control; consider temporary feeding separation, according to rate of responding
Aversion to mask or touchscreen Increase exploration of the mask and screen by applying food reward on the mask (e.g. peanut butter, pellets or other)
Excessive fighting in home cage Monitor home cage and general health of animal, separate if necessary
Stressors in housing room (e.g. noise) Make frequent observations of room and cage, move if necessary
Poor learning ability Exclusion may be necessary
Abrupt decline in performance and/or trial completion Touchscreen error (e.g. non-responsiveness, not displaying images) Check physical connections, clean, run test program (if available), recalibrate, reboot the system
Reward delivery ceased or inconsistent Check for physical blockage/disconnection, check for interface error, replace reward dispenser
Initiation not detected Clean magazine photobeam, check physical connections, replace if faulty
Controlling system error (software or hardware) Check physical connections, reboot the system, change hardware if necessary
Animal appears to make unusually low/high number of beam crosses (Campden only) Infrared beam failure Clean infrared beam pathway, check position of infrared switch, replace faulty beams
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