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. 2014 Jan 6;30(8):1087–1094. doi: 10.1093/bioinformatics/btt742

Fig. 2.

Fig. 2.

Sequence designer algorithm comprised by three different steps described in the main text. Initially, a target combination of features is selected and then a sequence that is close (i.e. short Euclidean distance) to the desired target is chosen to serve as the template in the sequence evolution step. This last step applies successive mutations until it finds a sequence matching the target combination of features