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. Author manuscript; available in PMC: 2014 Apr 10.
Published in final edited form as: Biochemistry. 2012 Oct 29;51(44):8829–8843. doi: 10.1021/bi300783t

Figure 1.

Figure 1

Positions of mutated amino acid residues in the Pol β-DNA-dNTP ternary complex. The primer-template DNA is shown in magenta. The N-terminal lyase domain (green), fingers- (orange), palm- (cyan) and thumb- (yellow) subdomains of polymerase domain are named according to the original Pol β nomenclature (89, 90) in which the polymerase domain is likened to the left hand. The positions of mutated residues are shown in red spheres (centered at Cα atom); dCTP substrate is shown in stick model. Insets show mutated residues and surrounding residues and deoxynucleotides in stick model (colored by atom type: carbon – green; oxygen – red; nitrogen – blue; phosphorus – orange; magnesium – dark grey).