Table 2.

miRNAs involved in cardiac degeneration:

micro-RNA	Fold expression	Site of expression	Methodology	Reference
Acute myocardial infarction
mir-1 mir-133a mir-208b mir-4993p	Upregulated 300 times Upregulated 70 times Upregulated 3000 times Upregulated 250 times	Human Plasma	qRT-PCR	[37]
mir-223	Downregulated	Human Plasma	qRT-PCR	[33]
mir-21	Downregulated in infarcted cells Upregulated in border cells	Rat Myocytes	qRT-PCR	[32]
mir-122 mir-375	Downregulated	Human Plasma	qRT-PCR	[26]
mir-423-5p	Upregulated 3–10 fold	Human Plasma	qRT-PCR	[11]
mir-663-b, -1291, mir-306, -145	Downregulated Upregulated	Human PBMCs	Array	[12]
mir-328	Upregulated in plasma	Human plasma	qRT-PCR	[144]
Coronary Artery Disease
mir-17-92 cluster, -126, -145, -155, mir-133, -208a	Downregulated Upregulated	Human Plasma	Array	[27]
mir-92a, -126, - 133a, -208a, -499	Upregulated 2–20 fold, ACS vs CAD	Human Plasma	qRT-PCR	[116]
mir-134, -135a, - 147, -198, -370 mir-147	Upregulated 3.1–12 fold Downregulated 4 fold	Human PBMCs	qRT-PCR	[30]
mir-340, mir-624	Upregulated >1.5 fold	Human Platelets	Array	[31]
Heart failure
mir-24, -125b, - 195, -199a, -214	Upregulated 1.3–3 fold	Human left ventricle	Northern blots	[38]
mir-214 mir-19a/b	Upregulated 2–2.8 fold Downregulated 2–2.7 fold	Human left ventricle	Bead based hybridization	[39]
mir-29b, -142-3p mir-107, -125b, - 139, -142-5p, -497	Upregulated >2 fold Down regulated >2 fold	Human PBMCs	qRT-PCR	[145]
mir-125, -181b, - 214, -342	Upregulated	Human left ventricle	Array	[146]
mir-100, -195,	Upregulated	Human heart tissue	Array	[40]
mir-92, -133b mir-21, -129, -212	Downregulated Upregulated >1.5 fold	Human heart tissue	Array	[147]