Table 5.
Estimated hazard ratios and 95%CI for factors associated with HCRU during follow-up in the 332 HIV-infected children followed-up at the CePReF between 2004 – 2009. Abidjan. Côte d’Ivoire. Shared Frailty Models.
| Outpatient care | Inpatient care | |||||
|---|---|---|---|---|---|---|
| HR | IC95% | P | HR | IC95% | P | |
| Age at ART initiation | 0.028 | 0.895 | ||||
| <2 years | 1 | – | 1 | – | ||
| 2–3 years | 0.84 | [0.51 – 1.25] | 0.91 | [0.42 – 2.00] | ||
| 3 – 5 years | 0.95 | [0.64 – 1.41] | 1.06 | [0.53 – 2.09] | ||
| 5 – 10 years | 0.84 | [0.57 – 1.23] | 0.9 | [0.46 – 1.77] | ||
| ≥ 10 years | 0.49 | [0.31 – 0.78] | 0.72 | [0.33 – 1.55] | ||
| Gender: Male/Female | 1.02 | [0.79 – 1.32] | 0.95 | 0.82 | [0.54 – 1.25] | 0.498 |
| Caregiver | 0.458 | 0.106 | ||||
| Both parents | 1 | – | 1 | – | ||
| Mother alone | 1.06 | [0.76 – 1.48] | 0.96 | [0.54 – 1.71] | ||
| Father alone | 0.67 | [0.40 – 1.12] | 0.34 | [0.13 – 0.87] | ||
| Other | 1.14 | [0.80 – 1.62] | 1.08 | [0.60 – 1.96] | ||
| Distance from clinic | 0.042 | 0.018 | ||||
| > 5 kms | 1 | – | 1 | – | ||
| 5 – 20 kms | 0.97 | [0.70 – 1.35] | 1.8 | [1.05 – 3.11] | ||
| ≥ 20 kms | 0.65 | [0.47 – 0.90] | 0.69 | [0.39 – 1.23] | ||
| CD4 % | < 0.001 | <0.001 | ||||
| ≥ 25% | 1 | – | 1 | – | ||
| 15 – 25 % | 1.2 | [0.86 – 1.66] | 1.58 | [0.92 – 2.72] | ||
| < 15% | 1.84 | [1.32 – 2.56] | 2.74 | [1.58 – 4.78] | ||
| Cotrimoxazole | 0.34 | [0.21 – 0.53] | <0.001 | 0.29 | [0.14 – 0.58] | <0.001 |
| Variance of random effect, (SE) | 0.33 (0.10) | < 0.001 | 1.23 (0.35) | <0.001 | ||