Table 1.
FC | Drug (gm) | T + E (mL) | P407 (gm) | P188 (gm) | C934 (gm) | HPMC K-100 (gm) | MP (gm) | PP (gm) | D/W (mL) |
---|---|---|---|---|---|---|---|---|---|
Ft1 | 0.6 | 6 | 6 | — | — | 0.15 | 0.03 | 0.003 | 30 |
Ft2 | 0.6 | 6 | 4 | 2 | — | 0.15 | 0.03 | 0.003 | 30 |
Ft3 | 0.6 | 6 | 4.5 | — | 0.09 | 0.15 | 0.03 | 0.003 | 30 |
Ft4 | 0.6 | 6 | 6 | — | 0.03 | 0.15 | 0.03 | 0.003 | 30 |
Ft5 | 0.6 | 6 | 6 | — | 0.09 | 0.15 | 0.03 | 0.003 | 30 |
Ft6 | 0.6 | 6 | 6 | — | 0.15 | 0.15 | 0.03 | 0.003 | 30 |
Note: FC: formulation code, T: tween 80, E: ethanol, P407: poloxamer407, P188: poloxamer188, C934: carbopol934, HPMC K-100: hydroxypropyl methyl cellulose, MP: methyl paraben, PP: propyl paraben, and D/W: distilled water.